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Free Thyroxine (Free T4)

Free T4 is the unbound, active form of thyroxine — the main thyroid hormone. Used to confirm and characterise abnormal TSH results. Low free T4 with high TSH confirms overt hypothyroidism; the opposite confirms hyperthyroidism.

Category
Thyroid
Units
pmol/L
Reference range
9-19 pmol/L

What does a high Free Thyroxine result mean?

Overt hyperthyroidism, thyroiditis, excess thyroid hormone replacement.

What does a low Free Thyroxine result mean?

Overt hypothyroidism, severe non-thyroidal illness, pituitary dysfunction.

Why does Free Thyroxine matter?

Confirms what TSH suggests. Doesn't replace TSH as the first-line screen.

Want Free Thyroxine interpreted in the context of your full panel? Every FORM bloodwork tier covers it, with an MD walking you through the result.

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